Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
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Arch support insole OEM from Taiwan

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.ODM service for ergonomic pillows Thailand

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Indonesia eco-friendly graphene material processing

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.China insole ODM design and production

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Taiwan anti-bacterial pillow ODM production factory

A microscopy image of neural cells where fluorescent markers show different types of cells. Green marks neurons and axons, purple marks neurons, red marks dendrites, and blue marks all cells. Where multiple markers are present, colors are merged and typically appear as yellow or pink depending on the proportion of markers. Credit: Cortical Labs DishBrain reveals how human neurons work together to process information. New research shows that when neurons are given information about the changing world around them (task-related sensory input) it changes how they behave, putting them on edge so that tiny inputs can then set off ‘avalanches’ of brain activity, supporting a theory known as the critical brain hypothesis. The researchers, from Cortical Labs and The University of Melbourne, used DishBrain – a collection of 800,000 human neural cells learning to play Pong. The study was published recently in the journal Nature Communications It is the strongest evidence to date in support of a controversial theory of how the human brain processes information. According to the critical brain hypothesis, big complex behaviors are only made possible when neurons are so on edge that tiny inputs can set off “avalanches” of brain activity. This fine-balanced state is known as a “neural critical” state, and lies between two extremes – the runaway excitation seen in disorders such as epilepsy, and a coma state where signals stall. “It not only shows the network reorganizing into a near-critical state as it is fed structured information but that reaching that state also leads to better task performance,” says Dr. Brett Kagan, Chief Scientific Officer of biotech start-up Cortical Labs, which created DishBrain. “The results are astonishing, way beyond what we thought we would achieve.” The research adds a vital piece to the puzzle of the critical brain hypothesis. Forough Habibollahi, first author of the study. Credit: Forough Habibollahi Key Findings and Implications Until now, there has been little experimental evidence demonstrating whether criticality is a general feature of biological neuronal networks or whether it is related to informational load. “Our results suggest that near-critical network behavior emerges when the neural network is engaged in a task but not when left unstimulated,” says Dr. Kagan. However, Dr. Kagan’s research shows that criticality alone is insufficient to drive learning by a neural network. “Learning requires a feedback loop, where the network is given additional information about the consequences of an action,” says Dr. Kagan. The latest research underlines the potential for DishBrain to help unlock the secrets of the human brain and how it works, which is not possible with animal models. “Usually to study the brain, especially on the scale of neurons, researchers have to use animal models, but in doing so, there are lots of difficulties and one can only have a limited number of subjects,” says first author Dr. Forough Habibollahi, a research fellow at Cortical Labs. “So when I saw DishBrain’s unique ability to answer different types of questions in a way nobody else could, I was super excited to start this project and join the team.” Applications and Future Possibilities Doctors also see great potential for the research to help discover treatments for crippling brain diseases. “The DishBrain criticality project has been an amazing collaborative experience between Cortical Labs, Biomedical Engineering and Neurology,” says paper author Dr. Chris French, leader of the Neural Dynamics Laboratory at the University of Melbourne’s Department of Medicine. “The critical dynamics of the DishBrain neurons should provide key biomarkers for diagnosis and treatment of a range of neurological diseases from epilepsy to dementia,” he says. By building a living model brain, scientists will be able to experiment using real brain function rather than flawed analogous models like a computer to not only explore brain function but also to test how drugs affect it. The research also has the potential to solve challenges facing brain-computer interfaces that could restore functions lost as a result of neural damage, says Professor Anthony Burkitt, an author on the paper and Chair of Bio Signals and Bio-Systems of the University of Melbourne’s Biomedical Engineering Department. “A key feature of the next generation of neural prostheses and brain-computer interfaces that we currently researching involves utilizing real-time closed-loop strategies,” he says. “So the results of this study could have important implications for understanding how these control and stimulation strategies interact with the neural circuits in the brain.” “This field of biological brain modeling is in its infancy but opens the way for a whole new area of science,” Dr. Kagan says. Reference: “Critical dynamics arise during structured information presentation within embodied in vitro neuronal networks” by Forough Habibollahi, Brett J. Kagan, Anthony N. Burkitt and Chris French, 30 August 2023, Nature Communications. DOI: 10.1038/s41467-023-41020-3 Abstract Critical dynamics arise during structured information presentation within embodied in vitro neuronal networks Forough Habibollahi, Brett J. Kagan, Anthony N. Burkitt, and Chris French Understanding how brains process information is an incredibly difficult task. Amongst the metrics characterizing information processing in the brain, observations of dynamic near-critical states have generated significant interest. However, theoretical and experimental limitations associated with human and animal models have precluded a definite answer about when and why neural criticality arises with links from attention, to cognition, to consciousness. To explore this topic, we used an in vitro neural network of cortical neurons that was trained to play a simplified game of ‘Pong’ to demonstrate Synthetic Biological Intelligence (SBI). We demonstrate that critical dynamics emerge when neural networks receive task-related structured sensory input, reorganizing the system to a near-critical state. Additionally, better task performance correlated with proximity to critical dynamics. However, criticality alone is insufficient for a neuronal network to demonstrate learning in the absence of additional information regarding the consequences of previous actions. These findings offer compelling support that neural criticality arises as a base feature of incoming structured information processing without the need for higher-order cognition.

A new study reveals that 4% of Icelanders carry genotypes linked to serious diseases, impacting their lifespan. The study, which analyzed 58,000 whole-genome sequenced Icelanders, found that actionable genotypes, particularly those predisposing individuals to cancer and cardiovascular diseases, significantly shorten life expectancy. These findings have led to a national precision medicine initiative in Iceland, underscoring the potential of genomic data in improving healthcare and patient outcomes. Scientists at deCODE genetics, a subsidiary of Amgen, have published a study exploring the relationship between specific genotypes found in the Icelandic population and their impact on lifespan. This study has inspired the Icelandic government to initiate a comprehensive precision medicine program. Precision medicine delivery relies heavily on extensive data in genomics, transcriptomics, and proteomics, areas where Icelanders have a unique advantage because they behold an unprecedented amount of such data. The study, recently published in the New England Journal of Medicine, focuses on genotypes that increase the risk of a disease for which preventive or therapeutic measures have been established. These genotypes are termed actionable genotypes. The scientists used a population-based data set, consisting of 58,000 whole-genome sequenced Icelanders, to assess the fraction of individuals carrying actionable genotypes. Utilizing a list of 73 actionable genes from the guidelines from the American College of Medical Genetics and Genomics (ACMG), the scientists found that 4% of Icelanders carry an actionable genotype in one or more of these genes. The diseases caused by these genotypes include cardiovascular, cancer, and metabolic diseases. Impact of Actionable Genotypes on Lifespan The study assessed the relationship between actionable genotypes and the lifespan of their carriers. The largest effect was observed among carriers of cancer-predisposing genotypes, which had three years shorter median survival than non-carriers. A pathogenic variant in BRCA2, predisposing to breast, ovarian, and pancreatic cancer, shortened lifespan by seven years, and a variant in LDLR, which causes high levels of cholesterol and cardiovascular disease, shortened lifespan by six years. “Our results suggest that the actionable genotypes identified in our study, which are all predicted to cause serious disease, may have a drastic effect on lifespan,” said Patrick Sulem author on the paper and scientist at, deCODE genetics. Three authors on the paper, Kari Stefansson, Patrick Sulem, and Brynjar O Jensson. Credit: deCODE Genetics The results showed that carriers of particular actionable genotypes were more likely to have died from the disease caused by these genotypes. Individuals with a pathogenic variant in BRCA2, have a seven-fold risk of dying from breast, ovarian, or pancreatic cancer. Furthermore, they are 3.5 times more likely to develop prostate cancer and 7 times more likely to die from prostate cancer than those who do not carry the variant. The researchers determined that 1 in 25 individuals carried an actionable genotype and have, on average, a shortened lifespan. “The identification and disclosure of actionable genotypes to participants can guide clinical decision-making, which may result in improved patient outcomes. This knowledge therefore has significant potential to mitigate disease burden for individuals and society as a whole” said Kari Stefansson, author of the paper and CEO of deCODE genetics. Reference: “Actionable Genotypes and Their Association with Life Span in Iceland” by Brynjar O. Jensson, Gudny A. Arnadottir, Hildigunnur Katrinardottir, Run Fridriksdottir, Hannes Helgason, Asmundur Oddsson, Gardar Sveinbjornsson, Hannes P. Eggertsson, Gisli H. Halldorsson, Bjarni A. Atlason, Hakon Jonsson, Gudjon R. Oskarsson, Arni Sturluson, Sigurjon A. Gudjonsson, Gudmundur A. Thorisson, Florian Zink, Kristjan H.S. Moore, Gunnar Palsson, Asgeir Sigurdsson, Adalbjorg Jonasdottir, Aslaug Jonasdottir, Magnus K. Magnusson, Anna Helgadottir, Valgerdur Steinthorsdottir, Julius Gudmundsson, Simon N. Stacey, Rafn Hilmarsson, Isleifur Olafsson, Oskar T. Johannsson, David O. Arnar, Jona Saemundsdottir, Olafur T. Magnusson, Gisli Masson, Bjarni V. Halldorsson, Agnar Helgason, Hreinn Stefansson, Ingileif Jonsdottir, Hilma Holm, Thorunn Rafnar, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Kari Stefansson and Patrick Sulem, 7 November 2023, New England Journal of Medicine. DOI: 10.1056/NEJMoa2300792

“Nanowires” produced by Geobacter in response to an electric field applied to electricity-producing biofilms. These nanowires are composed of cytochrome OmcZ and show 1000-fold higher conductivity and 3-times higher stiffness than the nanowires of cytochrome OmcS important in natural environments, allowing bacteria to transport electrons over 100-times their size. Credit: Sibel Ebru Yalcin. Design: Ella Maru Studio An ultra-stable protein nanowire made by bacteria provides clues to combating climate change. Rapid global warming poses a severe and immediate threat to life on Earth. Rising temperatures are caused in part by atmospheric methane, which is 30 times more potent than CO2 at trapping heat. Microbes produce half of this methane and as temperatures continue to rise, microbial growth is accelerated, leading to a higher production of greenhouse gases than can be absorbed by plants. This weakens the Earth’s ability to act as a carbon sink and contributes to a rise in global temperatures. A potential solution to this vicious circle could be another kind of microbe that eats up to 80% of methane flux from ocean sediments that protect the Earth. How microbes serve as both the biggest producers as well as consumers of methane has remained a mystery because they are very difficult to study in the laboratory. In the journal Nature Microbiology, surprising wire-like properties of a protein highly similar to the protein used by methane-eating microbes are reported by a Yale University team led by Yangqi Gu, and Nikhil Malvankar, of Molecular Biophysics and Biochemistry at Microbial Sciences Institute. The team had previously shown that this protein nanowire shows the highest conductivity known to date, allowing the generation of the highest electric power by any bacteria. But to date, no one had discovered how bacteria make them and why they show such extremely high conductivity. Nanowire’s Atomic Structure Using cryo-electron microscopy, Yangqi and the team were able to see the nanowire’s atomic structure and discover that hemes packed closely to move electrons very fast with ultra-high stability. It also explains how these bacteria can survive without oxygen-like membrane-ingestible molecules and form communities that can send electrons over 100 times bacterial size. Yangqi and the team also built nanowires synthetically to explain how bacteria make nanowires on demand. “We are using these heme wires to generate electricity and to combat climate change by understanding how methane-eating microbes use similar heme wires,” Malvankar said. Reference: “Structure of Geobacter cytochrome OmcZ identifies mechanism of nanowire assembly and conductivity” by Yangqi Gu, Matthew J. Guberman-Pfeffer, Vishok Srikanth, Cong Shen, Fabian Giska, Kallol Gupta, Yuri Londer, Fadel A. Samatey, Victor S. Batista and Nikhil S. Malvankar, 2 February 2023, Nature Microbiology. DOI: 10.1038/s41564-022-01315-5 Other authors are Malvankar Lab Members Matthew Guberman-Pfeffer, Vishok Srikanth, Cong Shen, Yuri Londer, Fadel Samatey with collaborators Prof. Victor Batista, Prof. Kallol Gupta, and Fabian Giska.

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