Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
🔗 Learn more or get in touch:
🌐 Website: https://www.deryou-tw.com/
📧 Email: shela.a9119@msa.hinet.net
📘 Facebook: facebook.com/deryou.tw
📷 Instagram: instagram.com/deryou.tw
China foot care insole ODM expert
Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Graphene insole OEM factory Thailand
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Indonesia athletic insole OEM supplier
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam insole ODM service provider
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Latex pillow OEM production in Thailand
Neuroscientists suggest that “forgetting” might be a form of learning that benefits flexible behavior in dynamic environments, and their experimental tests demonstrate that memories are not truly lost but are stored in engrams that can be reactivated. Their findings, which have implications for conditions like Alzheimer’s disease, show that memories can be retrieved through both natural and artificial cues. New research shows that forgetting is an adaptive, reversible process where memories remain stored but become inaccessible, offering hope for memory-related disorders. Neuroscientists have unveiled initial findings from experiments investigating the concept that “forgetting” might not be a bad thing, and that it may represent a form of learning – and outline results that support their core idea. Previously, these scientists proposed that changes in our ability to retrieve certain memories stem from environmental feedback and predictability. They argued that instead of being a flaw, forgetting could be an intentional characteristic of the brain, enabling it to adaptively engage with ever-changing surroundings. Forgetting as an Evolutionary Advantage In a changing world like the one we and many other organisms live in, forgetting some memories would be beneficial, they reasoned, as this can lead to more flexible behavior and better decision-making. If memories were gained in circumstances that are not wholly relevant to the current environment, forgetting them could be a positive change that improves our well-being. In a paper published in the leading international journal Cell Reports, they present the first in a series of new experimental studies where the effect of natural, “everyday” forgetting was investigated with respect to how normal forgetting processes affect particular memories in the brain. The team studied a form of forgetting called retroactive interference, where different experiences occurring closely in time can cause the forgetting of recently formed memories. In their study, mice were asked to associate a specific object with a particular context or room, and then recognize that an object that was displaced from its original context. However, mice forget these associations when competing experiences are allowed to ‘interfere’ with the first memory. Forgetting may be a functional feature of the brain, allowing it to interact dynamically with a dynamic environment. Credit: Dr. Nora Raschle To study the result of this form of forgetting on memory itself, the neuroscientists genetically labeled a contextual “engram” (a group of brain cells that store a specific memory) in the brains of these mice, and followed the activation and functioning of these cells after forgetting had happened. Crucially, using a technique called optogenetics they found that stimulation of the engram cells with light retrieved the apparently lost memories in more than one behavioral situation. Furthermore, when the mice were given new experiences that related to the forgotten memories, the ‘lost’ engrams could be naturally rejuvenated. How Memory Interference Shapes Recall Dr. Tomás Ryan, Associate Professor in the School of Biochemistry and Immunology and the Trinity College Institute of Neuroscience at Trinity College Dublin, is the lead author of the just-published journal article. Dr. Ryan, whose research team is based in the Trinity Biomedical Sciences Institute (TBSI), said: “Memories are stored in ensembles of neurons called ‘engram cells’ and successful recall of these memories involves the reactivation of these ensembles. By logical extension, forgetting occurs when engram cells cannot be reactivated. However, it is increasingly becoming clear that the memories themselves are still there, but the specific ensembles are not activated and so the memory is not recalled. It’s as if the memories are stored in a safe but you can’t remember the code to unlock it.” Dr. Livia Autore, Irish Research Council (IRC) Postgraduate Scholar, who spearheaded this work in the Ryan Lab in Trinity, added: “Our findings here support the idea that competition between engrams affects recall and that the forgotten memory trace can be reactivated by both natural and artificial cues as well as updated with new information. The continuous flow of environmental changes leads to the encoding of multiple engrams that compete for their consolidation and expression. “So while some may persist undisturbed, some will be subjected to interference by new incoming and prevailing information. However, the interfered memories can still be reactivated by surrounding cues leading to memory expression or by misleading or novel experiences ending up in an updated behavioral outcome.” Implications for Memory Disorders Like Alzheimer’s Because we now know that “natural forgetting” is reversible in certain circumstances, this work has significant implications for disease states – such as in people living with Alzheimer’s disease for example, where these everyday forgetting processes may be mistakenly activated by brain disease. Reference: “Adaptive expression of engrams by retroactive interference” by Livia Autore, James D. O’Leary, Clara Ortega-de San Luis and Tomás J. Ryan, 16 August 2023, Cell Reports. DOI: 10.1016/j.celrep.2023.112999 The study was funded by the European Research Council, the Canadian Institute for Advanced Research, the Irish Research Council, and the Science Foundation Ireland.
Shining a light on internal clocks – the bacterium Bacillus subtilis. Credit: Professor Ákos Kovács, Technical University of Denmark Researchers found that Bacillus subtilis has a circadian rhythm, adjusting gene activity based on light and temperature. This finding opens new doors in medicine and biotechnology. Humans have them, so do other animals and plants. Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth. The research answers a long-standing biological question and could have implications for the timing of drug delivery, biotechnology, and how we develop timely solutions for crop protection. Biological clocks or circadian rhythms are exquisite internal timing mechanisms that are widespread across nature enabling living organisms to cope with the major changes that occur from day to night, even across seasons. Existing inside cells, these molecular rhythms use external cues such as daylight and temperature to synchronize biological clocks to their environment. It is why we experience the jarring effects of jet lag as our internal clocks are temporarily mismatched before aligning to the new cycle of light and dark at our travel destination. A growing body of research in the past two decades has demonstrated the importance of these molecular metronomes to essential processes, for example, sleep and cognitive functioning in humans, and water regulation and photosynthesis in plants. Although bacteria represent 12% biomass of the planet and are important for health, ecology, and industrial biotechnology, little is known of their 24hr biological clocks. Previous studies have shown that photosynthetic bacteria that require light to make energy have biological clocks. But free-living non-photosynthetic bacteria have remained a mystery in this regard. Discovering Circadian Rhythms in Bacillus subtilis In this international study, researchers detected free-running circadian rhythms in the non-photosynthetic soil bacterium Bacillus subtilis. The team applied a technique called luciferase reporting, which involves adding an enzyme that produces bioluminescence that allows researchers to visualize how active a gene is inside an organism. They focused on two genes: firstly, a gene called ytvA which encodes a blue light photoreceptor, and secondly an enzyme called KinC that is involved in inducing the formation of biofilms and spores in the bacterium. They observed the levels of the genes in constant dark in comparison to cycles of 12 hours of light and 12 hours of dark. They found that the pattern of ytvA levels were adjusted to the light and dark cycle, with levels increasing during the dark and decreasing in the light. A cycle was still observed in constant darkness. Researchers observed how it took several days for a stable pattern to appear and that the pattern could be reversed if the conditions were inverted. These two observations are common features of circadian rhythms and their ability to “entrain” to environmental cues. They carried out similar experiments using daily temperature changes; for example, increasing the length or strength of the daily cycle, and found the rhythms of ytvA and kinC adjusted in a way consistent with circadian rhythms, and not just simply switching on and off in response to the temperature. Bacteria Know What Time It Is “We’ve found for the first time that non-photosynthetic bacteria can tell the time,” says lead author Professor Martha Merrow, of LMU (Ludwig Maximilians University) Munich. “They adapt their molecular workings to the time of day by reading the cycles in the light or in the temperature environment.” “In addition to medical and ecological questions, we wish to use bacteria as a model system to understand circadian clock mechanisms. The lab tools for this bacterium are outstanding and should allow us to make rapid progress,” she added. Implications for Medicine, Ecology, and Biotechnology This research could be used to help address such questions as: is the time of day of bacterial exposure important for infection? Can industrial biotechnological processes be optimized by taking the time of day into account? And is the time of day of anti-bacterial treatment important? “Our study opens doors to investigate circadian rhythms across bacteria. Now that we have established that bacteria can tell the time we need to find out the processes that cause these rhythms to occur and understand why having a rhythm provides bacteria with an advantage,” says author Dr Antony Dodd from the John Innes Centre. Professor Ákos Kovács, co-author from the Technical University of Denmark adds that “Bacillus subtilis is used in various applications from laundry detergent production to crop protection, besides recently exploiting as human and animal probiotics, thus engineering a biological clock in this bacterium will culminate in diverse biotechnological areas.” Reference: “A circadian clock in a non-photosynthetic prokaryote” by Zheng Eelderink-Chen, Jasper Bosman, Francesca Sartor, Antony N. Dodd, Ákos T. Kovács and Martha Merrow, 8 January 2021, Science Advances. DOI: 10.1126/sciadv.abe2086
New miniature species on researcher’s palm. Credit: Lucas Machado Botelho/Projeto Dacnis Brachycephalus dacnis is the seventh species of flea toad to be identified and is slightly larger than only one closely related species found in southern Bahia, Brazil. The study, published by a team from the State University of Campinas, led the research. Some species in the genus Brachycephalus, known as flea toads, reach less than 1 cm in length as adults—making them even smaller than a fingernail, a Brazilian 50 cent coin, or a U.S. dime. The name of the new species, B. dacnis, pays tribute to Project Dacnis, a conservation, research and education NGO that maintains private areas of Atlantic Rainforest, including the one where the animal was found, in Ubatuba, on the coast of São Paulo state. “There are small toads with all the characteristics of large toads except for their size. This genus is different. During its evolution, it underwent what we biologists call miniaturization, which involves loss, reduction and/or fusion of bones, as well as fewer digits and absence of other parts of their anatomy,” said Luís Felipe Toledo, corresponding author of the article and a professor in the Institute of Biology (IB-UNICAMP). The study was part of the FAPESP-funded Thematic Project “From the natural history to the conservation of Brazilian amphibians”, and was also supported by FAPESP via a PhD scholarship awarded to Julia Ernetti, a co-author of the article. This is the seventh species of flea toad described in the genus Brachycephalus. Until recently, the genus was known mainly for brightly colored species with venom, such as the pumpkin toadlets B. rotenbergae, B. ephippium, and B. pitanga, but researchers are now particularly interested in the diminutive size of the flea toads. Although pumpkin toadlets are larger than flea toads, they have fewer anatomical structures. Curiously, for example, they are unable to hear their own vocalizations due to the lack of a tympanic middle ear, as shown by an article by Toledo et al. published in Scientific Reports in 2017. Diversity The researchers’ attention was drawn to the newly described species, B. dacnis, by its vocalizations. It has the same morphology as another species, B. hermogenesi. Both have yellowish-brown skin, live in leaf litter, do not have tadpoles but emerge from their eggs as fully formed miniatures of the adult morphology, and occur in the same region. Their calls are different, however. DNA sequencing confirmed that B. dacnis was indeed a new species. However, a visit to Picinguaba, a district of Ubatuba where the specimens that permitted the description of B. hermogenesi were found, showed that B. dacnis also occurs there. “There may have been specimens belonging to the new species among those that served as a basis for describing B. hermogenesi in 1998,” Toledo said, suggesting the use of historical DNA sequencing tools to clear up any remaining uncertainty. Historical DNA is obtained from zoological museum and herbarium specimens. In their description of the new species, besides the requisite anatomical traits, the researchers included information about the skeleton and internal organs, as well as molecular data and details of its vocalizations. Descriptions of new species must include these details in order to distinguish them from others more precisely, given that many are cryptic and cannot be differentiated by external anatomy only. “The diversity of these miniature frogs may be far greater than we think. Hence the importance of describing as many traits and features as possible, to expedite the description process and get to work on conservation as quickly as possible,” Toledo said. Reference: “Among the world’s smallest vertebrates: a new miniaturized flea-toad (Brachycephalidae) from the Atlantic rainforest” by Luís Felipe Toledo, Lucas Machado Botelho, Andres Santiago Carrasco-Medina, Jaimi A. Gray, Julia R. Ernetti, Joana Moura Gama, Mariana Lucio Lyra, David C. Blackburn, Ivan Nunes and Edelcio Muscat, 25 October 2024, PeerJ. DOI: 10.7717/peerj.18265 The study was funded by the São Paulo Research Foundation.
DVDV1551RTWW78V
One-stop OEM/ODM solution provider Thailand 》where every detail is tailored to your brandis identityIndonesia insole OEM manufacturer 》your competitive edge in product performance and speedIndonesia graphene product OEM service 》simplifying complex ideas into market-ready products